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Detalle de la convocatoria

Fostering regulatory science to address combined exposures to industrial chemicals and pharmaceuticals: from science to evidence-based policies


This topic calls for applied research studies, demonstrating how new tools and methodological approaches from regulatory science that are workable in a regulatory context and are based on the latest scientific evidence, can be applied to identify, quantify and prevent harmful co-exposures to industrial chemicals and pharmaceuticals.

The applicants can address some or all of the following:

1. Development of innovative tools and analytical methods to detect and measure complex mixtures in the various environmental compartments;

2. Comparisons of different possible regulatory approaches to manage unintentional chemical mixtures and co-exposures, regarding effectiveness (improved protection of health and the environment), workability, cost-effectiveness and benefits to society and business;

3. Estimations of the degree to which current and possible future regulatory practices/approaches underestimate (or possibly occasionally overestimate) risks related to chemicals exposure (based on particular case studies, modelling and overall estimations);

4. Develop and apply modelling, statistical approaches and other relevant methods to identify and study the health impacts on human populations and the environment of exposures to combinations of different chemicals, e.g. through linking results from exposure monitoring with observed health effects;

5. Scientific case studies to identify safety margins for specific unintentional exposures to combination of chemicals to protect human and ecosystems health, while taking into account chronic exposures over longer time scales;

6. The possible effects on humans, in particular on vulnerable sub-populations, from combined (chronic) exposure to low levels of pharmaceuticals via the environment, taking account the inherent pharmacological properties and the potential for combined effects from co-exposures with other chemicals;

7. Combining and analysing EU data sources to generate insights on real-life and potential exposure combinations, typical exposure routes and uses;

8. Development, improvement and validation of models for predicting (chronic) exposure to combinations of chemicals, which can be applied in a premarket stage (risk assessment, risk management measures, including, e.g. authorisation and restriction of chemicals) and possibly already at the design phase of chemicals and materials as well as retrospectively (e.g. in the setting of environmental quality objectives).



Funding: between EUR 4 to 6 million.



Fecha Límite 26/01/2021

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